Available equipment & methods

Co-Authorships & Acknowledgments of the partnership will be agreed individually for each inquiry.

Equipment / Method	Address	Institution	Usage
Variable Pressure High Resolution Schottky Field Emission Scanning Electron Microscope	Paula Valdena 3-K1, Riga	BBCE - RTU BBI	Analysis of microstructure and chemical composition
X-ray micro-computed tomography	Paula Valdena 3-K1, Riga	BBCE - RTU BBI	Micro-computed tomography. Non-destructive 3D imaging and analysis
EasyMax 402 Advanced Synthesis Workstation for Chemical and Process Development	Paula Valdena 3-K1, Riga	BBCE - RTU BBI	Chemical and Process Development
Small microstructure analysis equipment (Scanning Electron Microscope (SEM)) VEGA LMS	Paula Valdena 3-K1, Riga	BBCE-RTU BBI	Analysis of microstructure
Ultra High Performance Liquid Chromatograph equipped with UV, Fluorescence and ELS detectors	Paula Valdena 3-K1, Riga	BBCE-RTU BBI	UHPLC method development and UHPLC analysis
Potentiometric titration station Mettler Toledo T90	Paula Valdena 3-K1, Riga	BBCE-RTU BBI	Acid-base titration; Redox titration; Ca2+ ion selective measurement; Titration in non-aqueous media; pH measurement
Freeze-dryer Martin Christ Beta 2-8 LSC plus	Paula Valdena 3-K1, Riga	BBCE-RTU BBI	Freeze-drying
Versatile gas sorption and degassing system set with 4 independent sample analysis stations for characterizing porous materials and powders	Paula Valdena 3-K1, Riga	BBCE-RTU BBI	Surface Area determination: Multipoint BET Method; Single Point BET Method Surface Area of Microporous Samples by Langmuir Method. Total Pore Volume and Average Pore Radius Pore Size Distributions (Mesopore and micropore)
Histology Equipment	Aizkraukles Str. 21, Riga	BBCE-LIOS-LPP	Tissue dissection, slicing, preparation, probing, staining, and analysis require tools that reliably produce high-quality samples.
Triple Quadrupole Liquid Chromatograph Mass Spectrometer (LC-MS/MS) Shimadzu LCMS-8060NX	Aizkraukles Str. 21, Riga	BBCE-LIOS-LPP	High sensitive and specific analytical technique that can precisely determine the identities and concentration of biomolecules, medicines, metabolites in various samples.
Super-Resolution STED/FLIM/FCS microscope Leica STELLARIS, SP8, SP8 MP	Aizkraukles Str. 21, Riga	BBCE-LIOS-LPP	Super-resolution imaging of live and fixed cells and tissues, diffusion analysis. The resolution of microscope is beyond the diffraction limit.
Asiga PRO 4K80 3D printer	Dzirciema street, 20 - BBCE	RSU Institute of Stomatology	Usable for production of anathomical and dental models, surgical guides, denture bases, temporaries, partial frameworks, IBT’s, dental crowns, dental bridges, custom trays and splints.
Apium M220 3D printer	Dzirciema street, 20 - BBCE	RSU Institute of Stomatology	The printer is developed to print parts of polyether ether ketone (PEEK) to the production of three-dimensional parts with low costs and high efficiency.
Aeris Research table-type X-ray diffractometer, 300 W	Paula Valdena 3-K1, Riga	BBCE-RTU BBI	A non-destructive technique that provides information on the crystallographic structure, chemical composition and physical properties of materials.
3DCeram C100 EASY LAB 3D printer	Dzirciema street, 20 - BBCE	RSU Institute of Stomatology	3D printer for creating small parts from varied ceramic slurries (e.g. zirconia, hydroxiapetite and alumina)
Rigaku CT lab HX	Dzirciema street 20, Riga, LV-1007	RSU Institute of Stomatology	For applications in materials and life science research, product development, failure analysis, and manufacturing quality control.
Design and manufacturing of personalized implants	Dziirciema street 20	RSU Institute of Stomatology	Design and manufacture of anatomical models from polymer materials. Design and manufacture of surgical cutting guides from polymer materials. Design and manufacture of personalized implants for hard tissue replacement from PEEK or bioceramic materials.
in vitro ADME services	Aizkraukles Str. 21, Riga	BBCE-LIOS-LPP	in vitro ADME testing for drug discovery and biomaterial research projects
in vivo PK-Tox services	Aizkraukles Str. 21, Riga	BBCE-LIOS-LPP	in vivo PK-Tox testing for drug discovery and biomaterial research projects
Thermo Scientific UltiMate 3000 Ultra High Performance Liquid Chromatograph equipped with UV-Vis detector	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University	Precise and efficient separation, identification, and quantification of complex chemical mixtures.
CAMAG® High-Performance Thin-Layer Chromatography System for qualitative analyses	Konsula Street 21, Riga, LV-1007	Rīga Stradiņš University	Qualitative analysis by enabling the separation, identification, and characterization of compounds, providing precise, reproducible results for fingerprinting, profiling, and comparative analysis of complex samples.
Zirbus Lyophilizer VACO 2	Konsula Street 21, Riga, LV-1007	Rīga Stradiņš University	Freeze-drying
Anton Paar Dynamic Light Scattering Instrument Litesizer DLS 700	Konsula Street 21, Riga, LV-1007	Rīga Stradiņš University	Precise characterization of particles with diameters in the range of 0.3 nm to 10 μm, by measuring their size distribution, zeta potential, and molecular weight.
Mettler Toledo Spectrophotometer UV7	Konsula iela 21, Riga, LV-1007	Rīga Stradiņš University	Measure the absorbance and transmittance of light in the UV and visible spectrum.
Atlas Autotouch® Press (Automatic Benchtop Laboratory Press)	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University	Pecise, repeatable compaction of powders (using pellet dies) or applying loads to other materials. The press is compatible with the full range of pressing tools, including pellet dies, film makers, and heated platens.
Virsa fibre-optic-coupled Raman spectrometer	Konsula Street 21, Riga, LV-1007	Rīga Stradiņš University	Non-destructive, remote chemical and structural analysis of materials by providing detailed molecular identification, polymorph characterization, stress/strain analysis, and chemical distribution mapping.
Rigaku MiniFlex benchtop X-ray diffractometer	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University	Crystalline phase identification (phase ID) and quantification, percent (%) crystallinity, crystallite size and strain, lattice parameter refinement, Rietveld refinement, and molecular structure.
Thermo Scientific Nicolet iS5 FT-IR Spectrometer	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University	Measuring the infrared absorption spectra of materials, enabling identification of molecular structures, functional groups, and chemical compositions.
Anton Paar GmbH Abbemat 350 Refractometer	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Refractive index measurements
Motic BA410E Binocular Microscope	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Binocular research microscope for transparent samples with camera and capability for image transfer to PC. Optical magnification up to 100x.
FlexaLAB Capsule Filler	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	To make powders, powder low dosages for inhalation or DPI, pellets, tablets, micro-tablets, capsule into capsule, liquids
Erweka GTB 2 Granulate Flow Tester	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Measurement of the flowability of powder and granules.
Thermo Scientific Inductively Coupled Plasma Triple Quadrupole Mass Spectrometer (iCAP TQ ICP-MS)	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	High-resolution mass spectrometer using inductively coupled plasma to ionize samples and a triple quadrupole configuration for highly sensitive, selective analysis of trace elements, isotopes in complex matrices, enabling precise detection, quantification
Malvern Panalytical Mastersizer3000 Laser Diffraction Analyzer	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Mastersizer 3000+ uses laser diffraction to measure the particle size and size distribution of materials.
Mini/Midi-Glatt Fluidized Bed System (FBD)	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Laboratory-scale and small production system used for granulation, coating, and drying of powders or particles.
Thermo Fisher Scientific Orbitrap Exploris 120 Mass Spectrometer (LC-MS)	Konsula Street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Precise identification and quantification of metabolites, proteins, lipids, and small molecules with exceptional sensitivity and dynamic range.
Bertin Technologies Precellys Evolution Sample Homogenizer	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	High-throughput sample homogenization, tissue grinding, and cell disruption.
KEM AT-710S Potentiometric Titrator	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Used for acid-base, redox, complexometric, and precipitation titrations to determine the concentration of analytes.
Linseis Messgeräte GmbH CHIP-DSC 100 Differential Scanning Calorimeter (DSC)	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	For measuring the heat flow associated with phase transitions, such as melting, crystallization, and glass transition, in materials to analyze thermal properties.
Copley FRV 100i Tablet Friability Tester	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Single friability test for tablets or abrasion drum.
Memmert HPP1060eco Constant Climate Chamber	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Stimulating controlled environmental conditions such as temperature, humidity, and light, to test the behavior and stability of materials.
King Dispenser Rx Tablet Counting Machine	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Semi-automatic dual-station tablet and capsule counting machine, designed for precise and efficient filling operations.
DEC MC DecJet 50 Micronizer	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	High-performance micronization of powders, enabling fine particle size reduction through jet milling.
Shimadzu Corporation Nexis GC-2030 Gas Chromatograph	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Separation, identification and quantitative analysis of volatile compounds.
Jeiotech OV4-30 Vacuum Oven	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Drying
SOTAX AG ATS Xtend Double UV Dissolution Tester	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Dissolution testing of pharmaceutical products, measuring the release of active ingredients in real-time using UV spectroscopy.
Sepha EZ Blister AutoFeed Blistering Machine	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Forming & Sealing Materials fed from reel holder using reel tensioning system. Cold forming capability.
Glatt GmbH GC-1 Tablet Coater	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Laboratory-scale coating system used for the coating of tablets and other solid dosage forms.
Mettler-Toledo HX204 Halogen Moisture Analyzer	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Determining the moisture content
LMH 11/12 Muffle Furnace	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Designed for testing aggressive charges.
Anton Paar GmbH MCR 102e Rheometer	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Measuring the flow and deformation behavior of materials, including liquids, pastes, and semi-solids, under varying temperature and shear conditions, providing detailed insights into their rheological properties.
Thermo Fisher Scientific Nicolet iS20 FTIR Spectrometer	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Identifying and characterizing chemical compounds by measuring their infrared absorption spectra, providing detailed information on molecular structure, functional groups, and interactions within samples.
Thermo Electron GmbH Pharma 11 Hot-Melt Extruder	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Extrusion process, where heat and pressure are applied to melt and shape drug formulations into solid dosage forms.
Fitzpatrik SLS Powder Processing Platform	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Powder processing
STYL’One Nano Compaction Simulator	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Scientists can use the flexibility to drive the punches at high velocity to replicate the pre and main compression of an R&D rotary tablet press. The powerful Alix data acquisition and analysis software allows to screen a formulation in less than 5 min.
UV-1900i UV-Vis Spectrophotometer	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Features a multi-language interface that is easy to use while providing a diversity of measurement modes such as photometric, spectrum, quantitation, kinetics, time-course, and bio-methods.
Thermo Fisher Scientific Vanquish CORE HPLC-UV/RI	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Separation, identification, and quantification of complex mixtures.
Korsch AG XL 100 Pro Rotary Tablet Press	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Pressing tablets
SOTAX AG SmartTest50 Semi-Automatic Tablet Testing System	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Weight, thickness, width, diameter/length and hardness of virtually all tablet shapes can be tested in full compliance with Pharmacopeia requirements.
Erweka SVM II Tapped Density Tester	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	100% USP/EP compliant tapped density testing
Mettler-Toledo V10S Karl Fischer Volumetric Titrator	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Titration
MeltPrep GmbH VCM Essentials (D25) Vacuum Compression Molding Device	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Vacuum compression molding
Erweka ZT 730 Disintegration Tester	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	The ERWEKA ZT 730 Series with cable-free AirBasket automatically determines the disintegration time of samples by using a system of magnets and sensors.
SOTAX AG ST50 WTDH Tablet Tester	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Measuring 5 parameters of tablets: Hardness, Length / Diameter, Width, Thickness, Weight / Mass
Glatt GmbH TMG High Shear Granulator	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Efficiently blend, granulate, and agglomerate powders into uniform granules under high shear forces.
Thermo Fisher Scientific Vanquish CORE HPLC-DAD	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	Separation, identification, and quantification of complex compounds in liquid samples.
Alexanderwerk GbmH WP 120 Pharma Roller Compactor	Konsula street 21, Riga, LV-1007	Rīga Stradiņš University, Laboratory of Finished Dosage Forms	With an integrated two-stage mill, this machine can process powder from 5 g to 50 kg per hour into different-sized and density granulates.
Evolution™ Pro UV-Vis Spectrophotometer	Paula Valdena 3-K1, Riga	BBCE-RTU BBI	UV-VIS spectroscopy
Fritsch Pulverisette 5 Planetary Ball Mill	Paula Valdena 3-K1	BBCE - RTU BBI	Milling
IKA EUROSTAR Power Control-Visc P7 Laboratory Reactor System	Paula Valdena 3-K1, Riga	BBCE - RTU BBI	Various chemical reactions, mixing, and homogenization processes on a 2-liter lab scale.
Interscience SCAN1200 Colony Counter	Paula Valdena 3-K1, Riga	BBCE - RTU BBI	Colony counter
Optika Microscopes Italy IM-5FLD fluorescence microscope	Paula Valdena 3-K1, Riga	BBCE - RTU BBI	Inverted fluorescence microscopy
TA instruments HR-20 Rheometer	Paula Valdena 3-K1, Riga	BBCE - RTU BBI	Rheology
Thermo Scientific Nicolet™ iS50 Fourier-Transform Infrared Spectrometer	Paula Valdena 3-K1, Riga	BBCE - RTU BBI	Fourier transform infrared spectroscopy (FTIR) analysis
Zeiss LSM 900 confocal microscope	Paula Valdena 3-K1, Riga	BBCE - RTU BBI	Imaging of live and fixed cells and tissues
3D bioprinter BioAssemblyBot 400, Advanced Solutions	Paula Valdena 3-K1, Riga	BBCE - RTU BBI	3D Bioprinting
Rotary evaporator Heidolph Laborota 4000 efficient	Paula Valdena 3-K1, Riga	BBCE RTU - BBI	Rotary evaporation
Particle size analyser Mastersizer 3000	Paula Valdena 3-K1, Riga	BBCE RTU - BBI	Measuring over the nanometer to millimeter particle size ranges. Suspensions, emulsion and dry powders can be measured.
Particle analyser Litesizer DLS 500 with dosing system	Paula Valdena 3-K1, Riga	BBCE RTU - BBI	Particle size, zeta potential and molecular mass analysis by measuring dynamic (DLS), electrophoretic (ELS) and static light scattering (SLS), respectively
Spectrophotometer (plate reader) Multiskan FC Thermofisher	Paula Valdena 3-K1, Riga	BBCE RTU - BBI	Cellular, nucleic acid and protein analysis, any ELISA assays such as cytotoxicity and cell proliferation assays as well as apoptosis assays etc.
Laboratory equipment for in vitro studies	Paula Valdena 3-K1, Riga	BBCE RTU - BBI	In vitro cell studies
Histology Laboratory Equipment	Paula Valdena 3-K1, Riga	BBCE RTU - BBI	Sample preparations for histology analysis.

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